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KMID : 0861019980130020069
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Korea Journal of Herbology
1998 Volume.13 No. 2 p.69 ~ p.76
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Inhibitory Effect of Immunoglobulin E production by Fructus Xanthii
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宋昊埈/Song, Ho-Joon
河顯秀/金台現/辛民敎/Ha, Hyun-Su/Kim, Tae-Hyeun/Shin, Min-Kyo
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Abstract
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We studies inhibitation effect of IgE release in the human B cell line(U266B1) and in the serum and spleen cell of mouse that has been immunized by antigen in order to find antiallergic effect of Fructus Xanthii (FX).
We have some findings as below.
1. IgE release in serum was inhibited dose dependently in case of administering FX orally in the mouse immunized.
2. IgE release in serum was inhibited dose dependently in case of injecting FX into abdomen in the mouse immunized.
3. When we take LPS+IL-4 way in the mouse spleen cell, IgE release was less than LPS way.
4. When we take LPS+IL-4 way in the human B cell line (U266B1), IgE release was less than LPS way.
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